Azelaic Acid

Azelaic Acid is a naturally occurring chemical belonging to the class of dicarboxylic acids. In skin care, it is most commonly used to treat acne.

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    azelaic acid

    Azelaic Acid


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      Estimated Delivery: May 25 – May 29


    Azelaic acid is a naturally occurring chemical of the dicarboxylic acid family. Acne treatment is its most popular application in skin care. However, it also inhibits the enzyme tyrosinase, mostly indirectly reducing melanin synthesis. Additionally, it seems to slow down the pace of DNA synthesis in aberrant melanocytes, which prevents them from proliferating. Melasma, lentigo maligna, and other hyperpigmentation issues have all been treated with it. Topical azelaic does not depigment naturally pigmented skin, freckles, age spots (solar lentigines), or nevi, or does so very minimally. It is frequently used in medications and cosmetics.

    Azelaic Acid Benefits:
    • Anti-acne – against mild to moderate acne.
    • Skin lightening
    • Anti-bacterial
    • Effective agent
    • Broad pH stability
    • Reduced hyperpigmentation

    APPLICATION: Skincare preparations that deal with acne as well as skin lightening
    INCI: Azelaic acid
    Solubility: Heated Water (About 50°C) (see Technical advice for more information)
    Assay: 99.0%
    Use rate: 1.0 to 10.0% (up to 20%)
    pH Stability: 3.5 – 6.0
    Storage: Store in a cool, dark, and dry place



    The heated water phase of emulsions is the optimal place to add azelaic acid because, while it dissolves readily at higher temperatures, it will crystallize at normal temperatures. Even after this, a suitable polymer with suspending power should be employed because, in larger concentrations, azelaic acid primarily serves as a dispersion agent. With the proper solvent or alcohol, smaller quantities can continue to be soluble. Additionally, this explains why its possible irritant profile exists. Recrystallization does not always indicate that an agent stops working, although even at concentrations of 15-20%, azelaic has a low bioavailability as a scattered substance.

    Solubilization and Stability in Gels

    Only a few solvents completely dissolved azelaic acid. Specifically, (poly)propylene glycol ethers and polyethylene glycol. And Butoxydiglycol, respectively. At high concentrations, these solvents allow the creation of transparent azelaic acid gels. The amount of azelaic acid that can be solubilized is still limited. It can also be stabilized by using other medications. To establish the proper balance, the formulating chemist will need to undertake tests.

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    This is a cosmetic raw material and is meant for external use only in cosmetic formulations.  As with all of our materials, it should not be taken internally. Naturishshop is not responsible for product compatibility. We advise everyone to test ingredients for performance, compatibility, and safety prior to committing to larger quantities. Keep all products out of reach of children. 
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